After the third shipment was lost at sea, the warehouse manager sighed in despair.

第三批貨在海上遺失後，倉庫經理絕望地嘆了口氣。

Many applicants feel despair after months of rejection emails, but persistence often pays off.

許多求職者在收到好幾個月的拒絕信後感到絕望，但堅持下去往往會有回報。

The investors' despair deepened when the company's stock fell another twenty percent overnight.

公司股價一夜之間又跌了百分之二十，投資人更加絕望了。